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- W2382679091 abstract "Objective To investigate the effects of garlic oil(GO)on n-hexane induced peripheral nerve injuries in rats.Methods Male SD rats were divided into four groups randomly(n=15 for each group):the control,the model,the low dose GO,and the high dose GO group.The low and high dose GO groups were administered intragastrically with GO(40 or 80 mg/kg·bw)and n-hexane(2500 mg/kg·bw)one hour after the GO treatment.The model group was administered with equivalent n-hexane.The treatments were performed five times per week for eight weeks.Neurobehavioral tests were performed every two weeks,including hind limb support,grip strength for forelimb,switching tail test and pressure pain test,and gait score was measured at the end of eight weeks.Results Compared with the control group(7.28 cm),the hind-limb-support index of the model group(9.58 cm)increased significantly(P0.05).But in the low(7.94 cm)and high(6.99 cm)dose GO groups,there was no significant change(P0.05).The grip-strength-for-forelimb indices of four groups were 10.0,3.0,6.0,and 8.0s;the indices of two GO groups were lower than that of the control group(P0.05)but higher than that of the model group(P0.05).Gait scores of two GO groups were better than that of the model group significantly at the end of eight weeks(P0.05).Conclusion GO has protective effects on n-hexane induced peripheral nerve injuries in rats." @default.
- W2382679091 created "2016-06-24" @default.
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- W2382679091 date "2010-01-01" @default.
- W2382679091 modified "2023-09-28" @default.
- W2382679091 title "Effects of garlic oil on n-hexane induced peripheral nerve injury in rats" @default.
- W2382679091 hasPublicationYear "2010" @default.
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