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- W2382698049 abstract "Objectives To observe the correlation between lipoprotein-associated phospholipase A2(LP-PLA2),CD4+ interferon(IFN)-γ+ positive cells and coronary thrombolysis in myocardial infarction (TIMI) blood flow in patients with acute coronary syndromes (ACS).Methods We selected 993 patients with ACS as objects (ACS group)and 580 persons examinated without coronary disease as controls (control group).All the patients were conducted percutaneous coronary interventions (PCI) and divided into A,B,C,D groups by TIMI blood flow.Peripharal blood samples were collected within 24 h.CD4+ IFN-γ+ positive cell levels were detected with flow cytometry (FCM),serum concentration of Lp-PLA2 was detected by enzyme-linked immunosorbent assay (ELISA).Results Serum concentration of Lp-PLA2 and CD4+ IFN-γ+ positive cells levels of ACS group were significantly higher than those in control group [(328.2±8.2) μg /L vs.(100.6±11.3)μg/L,P0.05;32.6%±5.8% vs.8.8%±3.2%,P0.05].Analysis of variance indicated that serum concentration of Lp-PLA2 and CD4+ IFN-γ+ positive cell levels of A,B,C,D group were significantly difference (P0.05).Moreover,serum concentration of Lp-PLA2 and CD4+ IFN-γ+ positive cell levels of A,B group were significantly higher than those in C,D group(P0.05).Multiple regression analysis indicated that TIMI blood flow was positive correlated with serum concentration of Lp-PLA2 and CD4+ IFN-γ+ positive cell levels (r=-0.693,P0.05;r=-0.584,P0.05).Conclusions Serum concentration of Lp-PLA2 and CD4 + IFN-γ + positive cell level may be good predictive factors for unstable plaque of ACS,and could be used to prognosticate of slow-flow or non-flow after PCI." @default.
- W2382698049 created "2016-06-24" @default.
- W2382698049 creator A5049012815 @default.
- W2382698049 date "2010-01-01" @default.
- W2382698049 modified "2023-09-23" @default.
- W2382698049 title "Correlation between lipoprotein-associated phospholipase A_2,CD4~+ IFN-γ~+ positive cells and coronary TIMI blood flow in patients with acute coronary syndrome" @default.
- W2382698049 hasPublicationYear "2010" @default.
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