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- W2382700628 abstract "Objective Rhinitis is divided into allergic rhinitis( AR) and non-allergic rhinitis( NAR). There are a lot of researches focusing on the lower airway of AR patients,but the inflammatory changes in the lower airway of NAR patients remain unclear. This study is to explore the inflammatory characteristics of the nasal and lower airway in NAR. Methods From January to December 2010,262 NAR patients and 264 healthy controls were enrolled in the present study. Medical history collection,skin prick test,nasal douche,induced sputum,nasal and bronchial provocation test were used to evaluate the inflammatory characteristics of NAR and the effects of inflammation on lower airway. Results The eosinophil in nasal douche and induced sputum were significantly increased in the NAR group than the control group( P 0. 01). In the NAR group,nasal provocation positive rate was 65. 6%,which was higher than 43. 6% in the control group( P 0. 01). In the NAR group,bronchial provocation positive rate was 6. 1%,which was higher than 1. 1% in the control group( P 0. 01). There was a significant correlation between the eosinophil in nasal douche and the induced sputum( r = 0. 454,P = 0. 000) in the NAR groups. Conclusion NAR patients were higher in EOS inflammation and airway hyperresponsiveness. In NAR patients,there is obvious correlation between the eosinophil in nasal and lower airway. When we were concerned about the status of nasal inflammation in patients with NAR,but also concerned about the status of the lower airway inflammation." @default.
- W2382700628 created "2016-06-24" @default.
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- W2382700628 date "2014-01-01" @default.
- W2382700628 modified "2023-09-24" @default.
- W2382700628 title "Analysis of the inflammation feature of the nasal and lower airway in patients with non-allergic rhinitis" @default.
- W2382700628 hasPublicationYear "2014" @default.
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