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- W2382799392 abstract "AIM: To explore the mechanism of osteosarcomainvasiveness and metastasis. METHODS: Using improvedtechniques of mRNA differential display, the differences ofgene expression between human osteosarcoma cell line SOSP-96o7 and its higher metastatic subpopulation cells SOSP-Mwere studied. RESULTS: Two differentially expressed se-quence tags, MSP2 and MSP3, were cloned from SOSP-96o7and analyzed. RT-PCR and northern blot verified their spe-cific expression in sosp-96o7. MSP2 was novel while MSP3shared 89% sequence homology with ZRP, which was identi-fied as a recently cloned transcription factor. These sequenceshave been logged in Genebank and the database accessionnumbers in EMBL are AF142579 and AF14258O, respective-ly. CONCLUSION: The expression of MSP2 and MSP3 areassociated with the suppression of metastatic property of os-teosarcoma." @default.
- W2382799392 created "2016-06-24" @default.
- W2382799392 creator A5075662294 @default.
- W2382799392 date "1999-01-01" @default.
- W2382799392 modified "2023-09-23" @default.
- W2382799392 title "Screening of tumor metastasis related genes from human osteosarcoma cells by mRNA differential display method" @default.
- W2382799392 hasPublicationYear "1999" @default.
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