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- W2382803721 abstract "Objective: To investigate the effects of PKC on spinal edema in experimental presyrinx state in rabbits. Methods: The experimental models were established in rabbits by intra-cisternal injection of Kaolin. The water content, pathological changs, PKC activity and blood spinal cord barrier function were measured with dry-wet measure, light microscope, substrate phosphorolysis kinase assay and Evans blue technique in 1、3、7、14、21d after operation respectively. Results: Water content assay and histological observation showed that spinal cord edema in Kaolin group animals appeared at the 1st day after kaolin injection, was more prominent at 3rd day, reached its peak at 7th day, and declined slowly after 3 weeks. Membrane PKC activity increased from 1st day, reached its peak at 7th day, lasted to 14th day, and then began to drop. Kytoplasm PKC activity showed opposite tendency. Evans blue content of spinal cord began to increase at the 3rd day greatly, reached its cusp at 7 day and lasted to the 21rd day. CONCLUSION: In experimental presyrinx state, transloactional activation of PKC involves in spinal edema from ischemia." @default.
- W2382803721 created "2016-06-24" @default.
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- W2382803721 date "2007-01-01" @default.
- W2382803721 modified "2023-09-25" @default.
- W2382803721 title "Effects of PKC on spinal edema in experimental presyrinx state in rabbits" @default.
- W2382803721 hasPublicationYear "2007" @default.
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