Matches in SemOpenAlex for { <https://semopenalex.org/work/W2382826400> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2382826400 abstract "Objective To discuss the expression of MRP and P-gp in the pancreas cancer tissue as well as the clinical significance.Methods The expression of MRP and P-gp in the pancreatic cancer tissue were examined by immunohistochemical stain.Results The positive expression rate of MRP in the pancreatic cancer was 53.33% and the positive expression rate was 10% in the normal pancreatic gland and the pancreatitis.The positive expression rate of MRP in the cancer of the pancreas's was significantly higher than that in the normal pancreatic gland and the pancreatitis(P0.05).The positive expression rate of P-gp in pancreatic cancer was 86.67%,and the positive expression rate in the normal pancreatic gland and the pancreatitis was 30%.The positive expression rate of P-gp in pancreatic cancer was significantly higher than that in the norm al pancreatic gland and the pancreatitis(P0.05).The positive expression of P-gp and MRP didn't show significant correlated with clinical findings including sex,age,tumor location,the degree of differentiation,aggressiveness,lymph rode metastasis and TNM stage of tumors(P0.05).Conclusion MRP,P-gp play an important role in multidrug resistance of tumors,its resistance mediated by different mechanisms.Clinical testing MRP,P-gp on the development of pancreatic cancer has important significance in formulating chemotherapy." @default.
- W2382826400 created "2016-06-24" @default.
- W2382826400 creator A5000835067 @default.
- W2382826400 date "2012-01-01" @default.
- W2382826400 modified "2023-09-24" @default.
- W2382826400 title "Expression and clinic significance of MRP and P-gp in patients with pancreatic cancer" @default.
- W2382826400 hasPublicationYear "2012" @default.
- W2382826400 type Work @default.
- W2382826400 sameAs 2382826400 @default.
- W2382826400 citedByCount "0" @default.
- W2382826400 crossrefType "journal-article" @default.
- W2382826400 hasAuthorship W2382826400A5000835067 @default.
- W2382826400 hasConcept C121608353 @default.
- W2382826400 hasConcept C126322002 @default.
- W2382826400 hasConcept C142724271 @default.
- W2382826400 hasConcept C143998085 @default.
- W2382826400 hasConcept C144369459 @default.
- W2382826400 hasConcept C204232928 @default.
- W2382826400 hasConcept C2775967933 @default.
- W2382826400 hasConcept C2778764654 @default.
- W2382826400 hasConcept C2779013556 @default.
- W2382826400 hasConcept C2780210213 @default.
- W2382826400 hasConcept C63363279 @default.
- W2382826400 hasConcept C71924100 @default.
- W2382826400 hasConcept C90924648 @default.
- W2382826400 hasConceptScore W2382826400C121608353 @default.
- W2382826400 hasConceptScore W2382826400C126322002 @default.
- W2382826400 hasConceptScore W2382826400C142724271 @default.
- W2382826400 hasConceptScore W2382826400C143998085 @default.
- W2382826400 hasConceptScore W2382826400C144369459 @default.
- W2382826400 hasConceptScore W2382826400C204232928 @default.
- W2382826400 hasConceptScore W2382826400C2775967933 @default.
- W2382826400 hasConceptScore W2382826400C2778764654 @default.
- W2382826400 hasConceptScore W2382826400C2779013556 @default.
- W2382826400 hasConceptScore W2382826400C2780210213 @default.
- W2382826400 hasConceptScore W2382826400C63363279 @default.
- W2382826400 hasConceptScore W2382826400C71924100 @default.
- W2382826400 hasConceptScore W2382826400C90924648 @default.
- W2382826400 hasLocation W23828264001 @default.
- W2382826400 hasOpenAccess W2382826400 @default.
- W2382826400 hasPrimaryLocation W23828264001 @default.
- W2382826400 hasRelatedWork W1608505699 @default.
- W2382826400 hasRelatedWork W1968609852 @default.
- W2382826400 hasRelatedWork W2019361675 @default.
- W2382826400 hasRelatedWork W2354088407 @default.
- W2382826400 hasRelatedWork W2356287323 @default.
- W2382826400 hasRelatedWork W2358816030 @default.
- W2382826400 hasRelatedWork W2359102989 @default.
- W2382826400 hasRelatedWork W2365882394 @default.
- W2382826400 hasRelatedWork W2366585642 @default.
- W2382826400 hasRelatedWork W2371223880 @default.
- W2382826400 hasRelatedWork W2379234917 @default.
- W2382826400 hasRelatedWork W2381552420 @default.
- W2382826400 hasRelatedWork W2382121673 @default.
- W2382826400 hasRelatedWork W2386798653 @default.
- W2382826400 hasRelatedWork W2390818398 @default.
- W2382826400 hasRelatedWork W2393871476 @default.
- W2382826400 hasRelatedWork W2410701838 @default.
- W2382826400 hasRelatedWork W2412501657 @default.
- W2382826400 hasRelatedWork W2415997330 @default.
- W2382826400 hasRelatedWork W2991218693 @default.
- W2382826400 isParatext "false" @default.
- W2382826400 isRetracted "false" @default.
- W2382826400 magId "2382826400" @default.
- W2382826400 workType "article" @default.