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- W2382856191 abstract "Objective:The killing activity of tumor killer cells against the MGC-803 gastric carcinoma cells was investigated Methods:The IL-6+CD3AK cells were prepared from the peripheral blood mononuclear cells (PBMCs) from the culture media containing rIL-6 with rIL-2 and anti-CD3Ab The other control groups were cultivated in rIL-6 only, in rIL-6 with anti-CD3ab, in rIL-2 only Each group was divided into four groups by the ratio of effect and target cells After 24 h and 48 h, the death rate of cancer cells was determined by MTT assay and trypan-blue exclusion, the morphologic changes were observed by various microscope Results:The killing activity of rIL-6+CD3AK cells was higher than those of the other groups(P0 05) comparing with control group The group with higher ratio of effect-target cells showed the stronger killing activity The tumor killer cells revolved round cancer cells and changed into rosette The microvilli of effect-target cells had appearance of combining and formatting caniniform When the target cells were observed with time interval,cells eventually showed piecemeal death Conclusion:The killing activity of rIL-6+CD3AK was stronger than that of LAK(in rIL-2 only) cells" @default.
- W2382856191 created "2016-06-24" @default.
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- W2382856191 date "2003-01-01" @default.
- W2382856191 modified "2023-09-25" @default.
- W2382856191 title "The killing activity of IL-6+CD3AK cells against the MGC-803 gastric carcinoma cell in vitro" @default.
- W2382856191 hasPublicationYear "2003" @default.
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