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- W2382875114 abstract "Objective To investigate the expressions of connexion-43(Cx43) among different prognostic groups of prostate cancer(Pca),and to evaluate the clinical value of Cx43 as a biomarker of the prognosis of Pca.Methods 136 cases of Pca were divided into three groups according to the prognosis.The Cx43 expressions in PCa tissues and 20 samples of BPH tissues were detected with immunohistochemical methods,and the results were statistically analysed.Results The positive expression rate of Cx43 in Pca was 52.94%,which was significantly lower than that in BPH(100%)(P0.01).The positive expression rates of Cx43 in the low risk group,medium risk group and high risk group were 88.24%,61.7% and 38.89% respectively,with statistical significance(P0.01).Conclusion The lower the expression of Cx43 is in Pca,the worse the prognosis,which indicates that Cx43 can serve as a biomarker to evaluate the biological behaviour and prognosis of prostate cancer." @default.
- W2382875114 created "2016-06-24" @default.
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- W2382875114 date "2012-01-01" @default.
- W2382875114 modified "2023-09-25" @default.
- W2382875114 title "The expression and clinical significance of connexin-43 in different prognostic groups of prostate cancer" @default.
- W2382875114 hasPublicationYear "2012" @default.
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