Matches in SemOpenAlex for { <https://semopenalex.org/work/W2382899103> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2382899103 abstract "Objective To investigate serum Clara cell secreted protein(CC16) concentrations in stable asthmatics, and the effect of inhaled glucocorticoids for more than one year on them. Methods Blood samples were collected from 22 stable asthmatic and 22 healthy non-smokers. After centrifugation, all serum samples were determined for CC16 concentrations using a human CC16 enzyme-linked immunosorbent assay(ELISA) kit. Results CC16 concentrations in sera were lower in stable asthmatic non-smokers than in healthy non-smokers [( 36.60± 9.45)μg/L vs ( 51.71± 10.36)μg/L, P 0.01]. Serum CC16 concentrations in stable asthmatics who had inhaled glucocorticoids for more than one year were higher than those who had never used glucocorticoids for therapy[( 43.49± 9.22) μg/L vs ( 32.33± 4.45) μg/L, P 0.05]. Conclusion CC16 concentrations in stable asthmatic non-smokers are lower than those in the healthy non-smokers. The endogenous anti-inflammatory activity of CC16 declines, further aggravating inflammatory responses in asthma. Glucocorticoids may inhibit airway inflammation by enhancing CC16 secretion. Further investigating the role of CC16 in the pathogenesis of asthma, and using rhCC16 in the therapy, may open up broad prospect for this disease." @default.
- W2382899103 created "2016-06-24" @default.
- W2382899103 creator A5087889769 @default.
- W2382899103 date "2004-01-01" @default.
- W2382899103 modified "2023-09-26" @default.
- W2382899103 title "Study on serum Clara cell secreted protein concentrations in stable asthmatics" @default.
- W2382899103 hasPublicationYear "2004" @default.
- W2382899103 type Work @default.
- W2382899103 sameAs 2382899103 @default.
- W2382899103 citedByCount "0" @default.
- W2382899103 crossrefType "journal-article" @default.
- W2382899103 hasAuthorship W2382899103A5087889769 @default.
- W2382899103 hasConcept C126322002 @default.
- W2382899103 hasConcept C132946820 @default.
- W2382899103 hasConcept C134018914 @default.
- W2382899103 hasConcept C153911025 @default.
- W2382899103 hasConcept C16613235 @default.
- W2382899103 hasConcept C203014093 @default.
- W2382899103 hasConcept C2776042228 @default.
- W2382899103 hasConcept C2776914184 @default.
- W2382899103 hasConcept C2780942790 @default.
- W2382899103 hasConcept C49039625 @default.
- W2382899103 hasConcept C71924100 @default.
- W2382899103 hasConcept C86803240 @default.
- W2382899103 hasConceptScore W2382899103C126322002 @default.
- W2382899103 hasConceptScore W2382899103C132946820 @default.
- W2382899103 hasConceptScore W2382899103C134018914 @default.
- W2382899103 hasConceptScore W2382899103C153911025 @default.
- W2382899103 hasConceptScore W2382899103C16613235 @default.
- W2382899103 hasConceptScore W2382899103C203014093 @default.
- W2382899103 hasConceptScore W2382899103C2776042228 @default.
- W2382899103 hasConceptScore W2382899103C2776914184 @default.
- W2382899103 hasConceptScore W2382899103C2780942790 @default.
- W2382899103 hasConceptScore W2382899103C49039625 @default.
- W2382899103 hasConceptScore W2382899103C71924100 @default.
- W2382899103 hasConceptScore W2382899103C86803240 @default.
- W2382899103 hasLocation W23828991031 @default.
- W2382899103 hasOpenAccess W2382899103 @default.
- W2382899103 hasPrimaryLocation W23828991031 @default.
- W2382899103 hasRelatedWork W2008508328 @default.
- W2382899103 hasRelatedWork W2026043829 @default.
- W2382899103 hasRelatedWork W2053102658 @default.
- W2382899103 hasRelatedWork W2143257156 @default.
- W2382899103 hasRelatedWork W2153447830 @default.
- W2382899103 hasRelatedWork W2188569268 @default.
- W2382899103 hasRelatedWork W2279677477 @default.
- W2382899103 hasRelatedWork W2299357942 @default.
- W2382899103 hasRelatedWork W2353769621 @default.
- W2382899103 hasRelatedWork W2357527949 @default.
- W2382899103 hasRelatedWork W2364494571 @default.
- W2382899103 hasRelatedWork W2365887887 @default.
- W2382899103 hasRelatedWork W2366279195 @default.
- W2382899103 hasRelatedWork W2369590111 @default.
- W2382899103 hasRelatedWork W2384647916 @default.
- W2382899103 hasRelatedWork W2385268324 @default.
- W2382899103 hasRelatedWork W2394238558 @default.
- W2382899103 hasRelatedWork W2399870282 @default.
- W2382899103 hasRelatedWork W2428675210 @default.
- W2382899103 hasRelatedWork W2989645515 @default.
- W2382899103 isParatext "false" @default.
- W2382899103 isRetracted "false" @default.
- W2382899103 magId "2382899103" @default.
- W2382899103 workType "article" @default.