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- W2382912652 abstract "To investigate the effect of Tanreqing-injection on immune function of mouse model of lung carcinoma treated by chemotherapy and discusse the immunoregulation function of the herb,mouse model of Lewis lung carcinoma was built,and mice were divided into the normal control group,the model control group,the chemotherapy group and the chemotherapy combined with Tanreqing-injection group,which were treated by corresponding strategy.Then the mice of all groups were sacrificed,and the peripheral blood,spleen and thymus were separated to detect peripheral blood lymphocytes count,spleen index(SI),and thymus index(TI).Furthermore,the proliferation of spleen lymphocytes and the cytotoxicity of NK were investigated by MTT method;the subsets of peripheral blood lymphocytes were detected by flow cytometry(FCM);the levels of IFN-γ,TNF-α,IL-4 in blood serum were measured by ELISA.Results showed the SI,TI and lymphocyte count of chemotherapy combined with Tanreqing-injection group were higher than those of the chemotherapy group obviously(P 0.05).And the chemotherapy combined with Tanreqing-injection group demonstrated notable improvement in peripheral-blood lymphocytes subset,proliferation of spleen lymphocytes and cytotoxicity of NK,as compared with the chemotherapy group(P 0.01).Meanwhile,the levels of IFN-γ and TNF-α in blood serum of chemotherapy combined with Tanreqing-injection group were higher than those of the chemotherapy(P 0.01).In conclusion,herbal Tanreqinginjection has certain protective effects on immune system of body with lung carcinoma treated by chemotherapy,and also possesses promotive effects on antitumor immunity." @default.
- W2382912652 created "2016-06-24" @default.
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- W2382912652 date "2014-01-01" @default.
- W2382912652 modified "2023-09-23" @default.
- W2382912652 title "The effects of Tanreqing-injection on immune function of Lewis lung carcinoma mouse model treated with chemotherapy" @default.
- W2382912652 hasPublicationYear "2014" @default.
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