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- W2382918033 abstract "Objective To investigate the application value of impulse oscillometry system( IOS) in pulmonary function assessment of silicosis patients. Methods Sixty-three patients with silicosis and twenty healthy controls were selected for IOS and pulmonary function test( PFT) examination respectively, analysing their difference and correlation. Results It was showed that:( 1) The PFT parameters such as FVC、FEV1and FEV1/ FVC were showed decreased with the rise of silicosis stage,there was no significant differences among control group,first-stage silicosis and second-stage silicosis( P 0. 05),but the significant differences could be observed between third-stage silicosis and other groups( P 0. 05).( 2) There were significant differences in IOS parameters including Z5、R5-R20、X5、Fres and AX between first-stage silicosis and controls( P 0. 05);the comparisons also showed statistics significance among control group and stage Ⅰ group or stage Ⅱ group( P 0. 05); IOS parameters in stage Ⅲ silicosis increased too as comparing with other groups.( 3) According to the pulmonary ventilation function,the silicosis patients could be divided into: normal,mild,moderate and severe groups,the IOS test showed that with the obstruction degree progression,the IOS parameters were also rised,and the differences among groups were significant( P 0. 05).( 4) All the IOS parameters except R20 and X5 were negatively correlated with FEV1、FEV1/ FVC,X5 was positively correlated with them( P 0. 05); correlation coefficient between FEV1/ FVC and IOS was more high. Conclusion The results suggested that:( 1) IOS including Z5、R5-R20、X5、Fres and AX has a certain clinical value in early finding abnormal pulmonary function in mild silicosis,which is better than that of PFT;( 2) IOS was well correlated with spirometric parameters,even much better than PFT in detecting airway resistance abnormality,that means it may play a supplementary role in pulmonary function assessment of silicosis patients." @default.
- W2382918033 created "2016-06-24" @default.
- W2382918033 creator A5077415100 @default.
- W2382918033 date "2014-01-01" @default.
- W2382918033 modified "2023-09-23" @default.
- W2382918033 title "Application of impulse oscillometry in the measurement of silicosis" @default.
- W2382918033 hasPublicationYear "2014" @default.
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