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- W2382921675 abstract "Objective To find out problems in clinical research designs and statistical analyses in studies of hospital infection in China so as to put forward appropriate countermeasures. Methods The CBMdisc was searched to find all the literature on hospital infection published in a series of national journals from 1997 to 1999. An analysis was made of the soundness and rationality of some common types of clinical research (case studies, cohort studies and clinical trials) in project designs and statistical analyses. Results 379 papers were collected, of which 165 belonged to the type of clinical research, accounting for 43.5%. Of these, 37 were case studies, 19(51.4%) of which were wrongly taken to be cohort studies analyzing risk factors. 60 were cohort studies, the most common type of research on hospital infection in China. Of these only 8(13.3%) had a relatively sound research design and statistical analysis. 27 were clinical trials, only 17(63%) of which had control groups and 8 mentioned random grouping, with none of them conducting result judgement via blinding, pre-trial calculation of the number of samples or baseline comparison between the trial and control groups. Conclusion There are such weak links as irrational designs, overly simple research contents, weak statistical concepts and too few quantitative analyses in the clinical research on hospital infection in China. These problems need to be stressed and solved promptly." @default.
- W2382921675 created "2016-06-24" @default.
- W2382921675 creator A5028930572 @default.
- W2382921675 date "2000-01-01" @default.
- W2382921675 modified "2023-09-23" @default.
- W2382921675 title "Analysis of current clinical research designs and statistical analyses in studies of hospital infection" @default.
- W2382921675 hasPublicationYear "2000" @default.
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