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- W2382938763 abstract "Objective: To observe the intervening effect of piercing and blood letting at twelve Jing points(十二井穴) of hands on the concentration of intra and extra cellular free calcium((Ca~(2+))i and((Ca~(2+))o) of) the neuron in rats with cerebral ischemia in super early stage,and investigate the mechanism of its(neuroprotective) effects on cerebral ischemic injury.Methods: Thirty Wistar rats were randomly divided into shamoperated group,model group and treatment group.The(Ca~(2+))o in ischemia area per minute within(20 minutes) after the ischemic injury was detected by the needle type Ca~(2+) selective pole.The(Ca~(2+))i of neuron in ischemic area at 20th minute after the ischemic injury was detected by using fluorescent indicator(fura2/AM).Results: Compared to the shamoperated rats,the(Ca~(2+))o of ischemic model rats decreased since 5 minutes(P0.05),then the declination was positively correlated with time(P0.01) till 20 th minute of ischemia,while the(Ca~(2+))i increased obviously(P0.01).Compared to the model group,the(extent) of (Ca~(2+))o declination in treatment group was restrained since 8 minutes(P0.05) and became more severe till the 18 th minute(P0.01);at the 20 th minute,the(Ca~(2+))i decreased obviously(P0.01).Conclusion: The piercing and blood letting at twelve Jing points of hands in treating cerebral ischemia in super early stage is able to rapidly regulate the(Ca~(2+))o and(Ca~(2+))i of neuron in ischemic area and restrains the over loading of calcium in the neuron.It has neuroprotective effects on cerebral ischemic injury." @default.
- W2382938763 created "2016-06-24" @default.
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- W2382938763 date "2005-01-01" @default.
- W2382938763 modified "2023-09-25" @default.
- W2382938763 title "Effect of acupuncture on concentration of intra and extra cellular free calcium of the neuron in rats with(cerebral) ischemia in super early stage" @default.
- W2382938763 hasPublicationYear "2005" @default.
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