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• W2382939005 abstract "Objective To explore the features of cognitive impairment among patients with acute ischemic stroke.Methods In this prospective study, data were collected consecutively from 220 in-patients at the Neurology Department of Guangzhou First People's Hospital from March 2011 to June 2012. These patients were assessed with both Montreal Cognitive Assessment(MoCA) and Mini-Mental State Examination(MMSE) at the day of enrollment. Simultaneously, a control group of 146 healthy individuals from matched background was also set up. Control subjects were enrolled from community centers, physical examination center in our hospital and some of them were relatives of the patients as well. The patients were classifi ed into subgroups based on the total scores of MoCA and MMSE, respectively. There are four subgroup: Group A(MMSE26, MoCA 23) with 93 patients, Group B(the scores of MMSE are between 26~27, MoCA 23) with 36 patients, Group C(MMSE 28, MOCA 23) with 24 patients, Group D(those with normal scores in both MMSE andMOCA) with 67 patients.Results Patients scored less than the controls overall on both the MMSE(25.07±3.99 vs 27.73±1.89) and MoCA(17.70±5.77 vs 23.96±3.44),(P0.05). There is no statistic difference in the naming subtests of MoCA in the two groups(patient group 3[2, 3], control group 3[2, 3], P=0.159). A comparison of the subtest scores of MoCA suggests that the subgroup A(visuospatial/executive function [1{0, 2}], naming [2{1, 3}], recall [1{0, 2}], attention [3{2, 5}], language [0{0, 0}], abstraction [0{0, 1}], orientation [4{3, 5}]) and subgroup B(visuospatial/executive function [1{1, 2}], naming [2{1, 3}], recall [2{0, 3}], attention [5{4, 6}], language [0{0, 0}], abstraction [1{1, 2}], orientation [6{5, 6}]) have worse performances than the control group(visuospatial/executive function [4{3, 5}], naming [3{2, 3}], recall [3{2, 4}], attention [6{5, 6}], language [2{1, 2}], abstraction [2{1, 2}], orientation [6{6, 6}])(P0.05), while subgroup C show decreased score in visuospatial/executive function(2[1, 3.75]), language(0[0, 0]) and recall(2[1, 3])(P0.05).Conclusion Patients with acute ischemic stroke suffered from cognitive impairment in all subdomains of MoCA except naming. Visuospatial/executive function, language and recall impairment are the main clinical features in patients with mild cognitive impairment who cannot be recognized by MMSE." @default.
• W2382939005 created "2016-06-24" @default.
• W2382939005 creator A5028012159 @default.
• W2382939005 date "2014-01-01" @default.
• W2382939005 modified "2023-09-23" @default.
• W2382939005 title "A Study of the Clinical Features of Cognitive Impairment among Patients with Acute Ischemic Stroke" @default.
• W2382939005 hasPublicationYear "2014" @default.
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