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- W2382960500 abstract "Objective :To investigate effect of Shizao Decoction in the rat model of Xuanyin(Pleural effusion). Methods :Seventy-two healthy Wistar rats were randomly divided into normal group(8),model group(32)and treatment group(32). Model group and treatment group,according to the injection of carrageenan after execute on time,were divided into 4 pleuritis groups(12,24,36,and 48 h groups respectively). General activities,urine volume,pleural fluid volume,pleural fluid leukocyte count and classification,and pathological changes in the pleur tissues were observed. Results :After injection of carrageenan,rat pleural cavity had a large number of exudates. The volume of pleural effusion reached the peak in 24 hour,and began to decline after 36 hours. Until 48 hours only a small amount of liquid exudation was left,treatment groups had similar rules,but compared with the model group,exudates reduced obviously(P0.05). Pleural effusion's total white blood cell count was elevated,and mainly were multinucleated cells. When the treatment group compared with the model group,the total white blood cells overall had a reduced tendency,but the individual group had no statistical significant difference(P0.05). Rat pleural pathological section results showed that the treatment groups' interstitial edema and leukocyte infiltration in the pleura were lighter than those of the model group at the same time point. Conclusions :Shizao Decoction has a positive therapeutic effect on Xuanyin(pleural effusion)and can reduce the volume of pleural fluid,the pleural effusion leukocyte count and pleural pleural tissue interstitial edema and inflammatory cell infiltration." @default.
- W2382960500 created "2016-06-24" @default.
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- W2382960500 date "2014-01-01" @default.
- W2382960500 modified "2023-09-23" @default.
- W2382960500 title "Intervention Effect of Shizao Decoction in Rat Model of Xuanyin(Pleural Effusion)" @default.
- W2382960500 hasPublicationYear "2014" @default.
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