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- W2383010486 abstract "A Streptomyce SC-4 with high antibacterial activation was screened,it was identified as Streptomyces griseofuscus. For enhance the antibacterialthe substances antibacterial substance fermentation conditions were optimized using single factor method,and the results showed that the optimal conditions were temperature 37 ℃,initial pH7,inoculum 6%,rotation speed 180 r/min and fermentation 5days. To separate and purify the antibacterial substance,the method of ammonium sulfate fractionation and HPLC were used. Finally,four active peaks were obtained with HPLC,the peak 1 is high and peak 4 is low. These maybe have some means for structure identification and new antibiotics development." @default.
- W2383010486 created "2016-06-24" @default.
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- W2383010486 date "2013-01-01" @default.
- W2383010486 modified "2023-09-26" @default.
- W2383010486 title "Optimization fermentation conditions and purification of the antibacterial substance produced by Streptomyces griseofuscus SC-4" @default.
- W2383010486 hasPublicationYear "2013" @default.
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