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- W2383051093 abstract "The effect of sodium quercetin monosulfate (SQMS) on the growth of HL-60 cells was studied by observing cytotoxicity, cell cycle progression, cytosolic free calcium level ([Ca 2+] i) and the activity of protein kinase CK2 of HL-60 cells. SQMS (20-120 μmol·L -1) inhibited the growth of HL-60 cells in a concentration-dependent manner, arrested HL-60 cells in G 0/G 1 phase, increased the [Ca 2+] i at 25-100 μmol·L -1 from (105±9) to (201±13)nmol·L -1, SQMS at 0.55-8.8 μmol·L -1 inhibited the activity of CK2 purified from HL-60 cells in a concentration-dependent manner. These results indicated that SQMS inhibited the growth of HL-60 cells, which may be due to its inhibition of the activity of CK2,the increase in [Ca 2+] i and inducing the differentiation of HL-60 cells." @default.
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- W2383051093 date "2000-01-01" @default.
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- W2383051093 title "Effect of sodium quercetin monosulfate on the growth of HL-60 cells" @default.
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