Matches in SemOpenAlex for { <https://semopenalex.org/work/W2383092741> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2383092741 abstract "Objective To assess the safety and immunogenicity of a new inactivated hepatitis A vaccine in children and adults. Methods 176 healthy children and 206 healthy adults with both HBsAg and hepatitis A IgG antibody negative selected from Mengshan County of Guangxi Zhuang Autonomous Region were randomly divided into 4 groups. 107 children(group A) and 131 adults(group B) were received 640EIU/ 1.0ml and 1440EIU/1.0ml of home-made inactivated hepatitis A vaccine (Institute of Medical Biology, Chinese Academy of Medical Sciences), 69 children (group C) and 75 adults (group D) were given 720 EIU/ 1. 0ml and1440EIU/ 1.0ml of inactivated hepatitis A vaccine (SmithKline, Beecham Biologicals) by 0, 6 month schedule.The local and systemic side-effects were recorded the first 72 hours after each vaccination. Seroconversion rate and geometric mean titer (GMT) of antibody to hepatitis A were tested at months 1, 6 and 7 after first dose of vaccination. Results Local and systemic side effects were not observed in all participants within 3 days after first dose vaccination and no elevation of ALT was found. One month after first dose of vaccination, the seroconversion rates and GMTs of anti - HAV IgG were 94.8% and 96.7% as well as 758.6mIU/ ml and, 3630.8 mIU/ ml in group A and B , respectively . One month after second dose of vaccination, the seroconversion rates of anti - HAV IgG of all 4 groups were 100% , the GMTs in group A and B ( 10471.2 mIU/ml and 12302.7 mIU/ml )were more higher than those in group C and D(3090.3 mIU/ml and 3388.4 mIU/ml) .Conclusion The home-made new inactivated hepatitis A vaccine was safe and highly immunogenic." @default.
- W2383092741 created "2016-06-24" @default.
- W2383092741 creator A5012226264 @default.
- W2383092741 date "2003-01-01" @default.
- W2383092741 modified "2023-09-24" @default.
- W2383092741 title "Safety and immunogenicity of a new inactivated hepatitis A vaccine in children and adults" @default.
- W2383092741 hasPublicationYear "2003" @default.
- W2383092741 type Work @default.
- W2383092741 sameAs 2383092741 @default.
- W2383092741 citedByCount "0" @default.
- W2383092741 crossrefType "journal-article" @default.
- W2383092741 hasAuthorship W2383092741A5012226264 @default.
- W2383092741 hasConcept C126322002 @default.
- W2383092741 hasConcept C159654299 @default.
- W2383092741 hasConcept C203014093 @default.
- W2383092741 hasConcept C22070199 @default.
- W2383092741 hasConcept C2522874641 @default.
- W2383092741 hasConcept C2775876817 @default.
- W2383092741 hasConcept C2776029263 @default.
- W2383092741 hasConcept C2777382497 @default.
- W2383092741 hasConcept C2777410769 @default.
- W2383092741 hasConcept C2777451964 @default.
- W2383092741 hasConcept C2780593183 @default.
- W2383092741 hasConcept C2780799908 @default.
- W2383092741 hasConcept C2780868878 @default.
- W2383092741 hasConcept C2781037505 @default.
- W2383092741 hasConcept C32611913 @default.
- W2383092741 hasConcept C71924100 @default.
- W2383092741 hasConceptScore W2383092741C126322002 @default.
- W2383092741 hasConceptScore W2383092741C159654299 @default.
- W2383092741 hasConceptScore W2383092741C203014093 @default.
- W2383092741 hasConceptScore W2383092741C22070199 @default.
- W2383092741 hasConceptScore W2383092741C2522874641 @default.
- W2383092741 hasConceptScore W2383092741C2775876817 @default.
- W2383092741 hasConceptScore W2383092741C2776029263 @default.
- W2383092741 hasConceptScore W2383092741C2777382497 @default.
- W2383092741 hasConceptScore W2383092741C2777410769 @default.
- W2383092741 hasConceptScore W2383092741C2777451964 @default.
- W2383092741 hasConceptScore W2383092741C2780593183 @default.
- W2383092741 hasConceptScore W2383092741C2780799908 @default.
- W2383092741 hasConceptScore W2383092741C2780868878 @default.
- W2383092741 hasConceptScore W2383092741C2781037505 @default.
- W2383092741 hasConceptScore W2383092741C32611913 @default.
- W2383092741 hasConceptScore W2383092741C71924100 @default.
- W2383092741 hasLocation W23830927411 @default.
- W2383092741 hasOpenAccess W2383092741 @default.
- W2383092741 hasPrimaryLocation W23830927411 @default.
- W2383092741 hasRelatedWork W1623582254 @default.
- W2383092741 hasRelatedWork W1977761218 @default.
- W2383092741 hasRelatedWork W2022090199 @default.
- W2383092741 hasRelatedWork W2036159402 @default.
- W2383092741 hasRelatedWork W2263957674 @default.
- W2383092741 hasRelatedWork W2347291076 @default.
- W2383092741 hasRelatedWork W2347617863 @default.
- W2383092741 hasRelatedWork W2350951505 @default.
- W2383092741 hasRelatedWork W2352637007 @default.
- W2383092741 hasRelatedWork W2353396766 @default.
- W2383092741 hasRelatedWork W2362128378 @default.
- W2383092741 hasRelatedWork W2363499710 @default.
- W2383092741 hasRelatedWork W2366030412 @default.
- W2383092741 hasRelatedWork W2369444852 @default.
- W2383092741 hasRelatedWork W2369646683 @default.
- W2383092741 hasRelatedWork W2379878811 @default.
- W2383092741 hasRelatedWork W2388122170 @default.
- W2383092741 hasRelatedWork W2392775640 @default.
- W2383092741 hasRelatedWork W2395441152 @default.
- W2383092741 hasRelatedWork W2977257810 @default.
- W2383092741 isParatext "false" @default.
- W2383092741 isRetracted "false" @default.
- W2383092741 magId "2383092741" @default.
- W2383092741 workType "article" @default.