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- W2383093063 abstract "The effects of electrical and chemical stimulation of paraventricular nucleus (PVN) of hypothalamus on gastric ischemia reperfusion injury (GI RI)were investigated in male SD rats whose celiac arteries were clamped for 30 min and reperfused 1 h by removal of the clamp. The results were as follows: ① Electrical stimulation of the PVN could obviously attenuate the GI RI; ② Microinjection of L glutamic acid into PVN could produce the similar effect to that of PVN stimulation; ③ Electrolytic lesion of the PVN could aggravate the GI RI; ④ NTS lesion could eliminate the effect of electrical stimulation of PVN on GI RI; ⑤ Hypophysectomy could not influence the effect of electrical stimulation of PVN on GI RI; ⑥ Vagotomy and sympathectomy both could increase the effect of PVN stimulation on GI RI. These results mentioned above indicate that the PVN participates in the development of GI RI and is a specific area in the CNS for exerting protective effects on the GI RI; the NTS , vagus and sympathetic nerve may be involved in regulative effects of PVN on GI RI, but it is independent of PVN hypophyseal pathway. [" @default.
- W2383093063 created "2016-06-24" @default.
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- W2383093063 date "2001-01-01" @default.
- W2383093063 modified "2023-09-25" @default.
- W2383093063 title "The neuroregulative mechanism of hypothalamic paraventricular nucleus on gastric ischemia-reperfusion injury in rats" @default.
- W2383093063 hasPublicationYear "2001" @default.
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