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- W2383174923 abstract "Objective To explore the status of oxidative stress in rats caused by 60 m simulated air repetitive divings.Methods Adult rats were placed in an animal chamber (700 kPa air, 60 min) twice daily for 3 days. Peripheral blood was sampled 1, 3 and 5 days after the final exposure. Activities of superoxide dismutase, catalase, glutathione peroxidase, gluta-~thione S -transferase and levels of glutathione, malondialdehyde in plasma were determined colorimetrily. Results After hyperbaric exposures, the activities of anti-oxidative enzymes were decreased significantly (P0.05 or P0.01), but these could be recovered in 3-5 days. Glutathione concentration decreased (P0.01) on the 3rd day after exposures, and reached to normal level on the 5th day. The level of malondialdehyde increased (P0.01) after exposures and was recovered on the 5th day. The effects of 147 kPa oxygen were similar to those of 700 kPa air. There were no significant changes after treatment with normoxic hyperbaric nitrogen. Conclusion Rats suffered severe oxidative stress from 60 m simulated air repetitive divings, which was caused mainly by the high partial pressure of oxygen in compressed air and could be recovered in 3-5 days." @default.
- W2383174923 created "2016-06-24" @default.
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- W2383174923 date "2005-01-01" @default.
- W2383174923 modified "2023-09-26" @default.
- W2383174923 title "Oxidative stress in rats induced by simulated air repetitive divings" @default.
- W2383174923 hasPublicationYear "2005" @default.
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