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- W2383210894 abstract "OBJECTIVE To observe the effects of tannin in Punica granatum L.on rats with nephritic syndrome induced by adriamycin.METHODS Sixty male Wistar rats were randomly divided into 6 groups:the normal control,the model group,the SLPH group,the SLPZ group,the SLPD group and the benazepril group,10 rats in each group.Rats in the latter 5 groups were made into nephrotic syndrome(NS) model by tail intravenous injection with adriamycin(6.0 mg.kg-1).Next day the SLPH、SPLZ and SPLD group were given with tannin(60 g.kg-1.d-1、40 g.kg-1.d-1、20 g.kg-1.d-1)for 28 days,respectively,while the benazepril group were given with benazepril.Urine protein、total protein、albumin、total cholesterol、triglyeride、creatinine、blood urea nitrogen were measured.The cortical tissues from the right kidney were treated for electron microscopy to observe the pathological changes.RESULTS The tannin in Punica granatum L.could reduce ADR-induced increase in urine protein excretion,total cholesterol and triglyceride,decrease in total protein with dose-effect relationship.CONCLUSION Tannin in Punica granatum L.can ameliorate renal function of ADR-induced nephritic syndrome rats." @default.
- W2383210894 created "2016-06-24" @default.
- W2383210894 creator A5032248377 @default.
- W2383210894 date "2010-01-01" @default.
- W2383210894 modified "2023-09-28" @default.
- W2383210894 title "Study on the protective effect of tannin in Punica granatum L. on rats with nephrotic syndrome induced by adriamycin" @default.
- W2383210894 hasPublicationYear "2010" @default.
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