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- W2383250345 abstract "Objective To evaluate the risk of trans fatty acids on heart diseases by Meta-analysis. MethodsRelated literatures were searched with subject words includingtrans fatty acids,sudden cardiac death,myocardial and coronary heart from electronic databases of Medline,EMBASE,Cochrane Library,China National Knowledge Infrastructure,Chongqing VIP Database and Wanfang Data,etc.With multivariate adjusted relative ratio(RR) or odds ratio(OR) and their 95% confidence interval(CI) as parameters,literatures included were analysed by fixed effect model of Meta-analysis after heterogeneity inspection. Results A total of 9 literatures were selected,including 6 cohort studies and 3 case-control studies.Combined RR between trans fatty acids intake and heart disease events and between trans fatty acids intake and fatal heart diseases were 1.234(95%CI 1.117-1.363,P=0.000) and 1.307(95%CI 1.113-1.535,P=0.001),respectively.Combined OR between trans fatty acids in subcutaneous fat and first myocardial infarction events was 1.560(95%CI 1.119-2.175,P=0.009).Sensitivity analysis revealed that the results of this Meta-analysis were stable. Conclusion Trans fatty acids may be a risk factor for heart diseases." @default.
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- W2383250345 date "2011-01-01" @default.
- W2383250345 modified "2023-09-28" @default.
- W2383250345 title "Meta-analysis of risk of trans fatty acids on coronary heart diseases" @default.
- W2383250345 hasPublicationYear "2011" @default.
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