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- W2383278248 abstract "Objective To investigate the clinical effect of aprepitant combing tropisetron on prevention of vomiting after cisplatin chemtherapy. Methods Sixty patients with malignant applied cisplatin-containing chemotherapy regimens in our hospital from June 1, 2014 to November 1, 2014 were selected and divided into experimental group(30 patients) and control group(30 patients). The control group were given tropisetron during chemotherapy, while the experimental group were given aprepitant and tropisetron. The two group's vomiting preventive effect was compared. Results The experimental group' vomiting preventive effect was better than the control group. The complete remission rates of vomiting in control group for acute period, delay period and the whole period were 86.7%, 70.0% and 66.7% respectively, and the difference was statistically signifi cant(P 0.05) by comparing with experimental group's 73.3%, 43.3% and 40.0%. There was not obviously statistically significant(P 0.05) for dry mouth, dizziness, headaches and other adverse reaction rates. Conclusion Aprepitant combining tropisetron treating to malignant tumors can be safely and effectively to prevent vomiting." @default.
- W2383278248 created "2016-06-24" @default.
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- W2383278248 date "2015-01-01" @default.
- W2383278248 modified "2023-09-26" @default.
- W2383278248 title "Analysis of the Effect of Aprepitant Combing Tropisetron on Prevention of Vomiting after Cisplatin Chemtherapy" @default.
- W2383278248 hasPublicationYear "2015" @default.
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