Matches in SemOpenAlex for { <https://semopenalex.org/work/W2383291301> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W2383291301 abstract "Objective:To investigate the neuroprotective effect of lithium on the gerbil forebrain ischemia. Methods: The gerbil forebrain transient ischemia model was established by clamping the bilateral common carotid arteries for 5 min. Forty-eight gerbils were randomly divided into group A (n = 24) and group B (n=24). Gerbils in group A were injected intraperitoneally with lithium, 5' mmol/kg, once a day for 5 days. Saline was used instead of lithium in group B as control. Both group A and B were further divided into 4 subgroups respectively according to whether the animals underwent ischemia and when they were killed. The subgroups in group A were: Ais3, undergoing ischemia and killed 3 days after operation; Ash3, sham-operated and killed 3 days after operation; Ais7, undergoing ischemia and killed 7 days after operation; Ash7, sham-operated and killed 7 days after operation. Similarly, the subgroups in groupB were: Bis3, Bsh3, Bis7, Bsh7; n = 6 in each subgroup. All the gerbils were perfusion-fixed and made into paraffin sections. Neurons in the hippocampal CA1 subfield were counted under light microscopy blindly. Results:The numbers of the pyramidal cells(cells/0. 04mm2) in the CA1 sudfield were: 15.8±3.31 in Ais3, 13.54±5.22 in Ais7, 11.81 ±4.58 in Bis3, 1.48± 1.55 in Bis7, 28. 17±4. 02 in Ash3, 28. 11±4. 14 in Ash7, 29. 64±5. 99 in Bsh3, 30.21 ±2.95 in Bsh7. The living neuron density in the CA1 area of subgroup Ais3 was significantly higher than that of subgroup Bis3 (P 0. 01) . Similarly the living neuron density of subgroup Ais7 was significantly higher than that of Bis7 (P 0. 01). Conclusion: Preconditioning with lithium can protect the gerbil forebrain from the delayed neuron death induced by ischemia." @default.
- W2383291301 created "2016-06-24" @default.
- W2383291301 creator A5030845731 @default.
- W2383291301 date "2003-01-01" @default.
- W2383291301 modified "2023-09-26" @default.
- W2383291301 title "A Pathological Survey of the Neuroprotective Effect of Preconditioning with Lithium on the Gerbil Forebrain Ischemia" @default.
- W2383291301 hasPublicationYear "2003" @default.
- W2383291301 type Work @default.
- W2383291301 sameAs 2383291301 @default.
- W2383291301 citedByCount "0" @default.
- W2383291301 crossrefType "journal-article" @default.
- W2383291301 hasAuthorship W2383291301A5030845731 @default.
- W2383291301 hasConcept C126322002 @default.
- W2383291301 hasConcept C134018914 @default.
- W2383291301 hasConcept C148762608 @default.
- W2383291301 hasConcept C25498285 @default.
- W2383291301 hasConcept C2777397205 @default.
- W2383291301 hasConcept C2778541603 @default.
- W2383291301 hasConcept C2780222073 @default.
- W2383291301 hasConcept C42219234 @default.
- W2383291301 hasConcept C541997718 @default.
- W2383291301 hasConcept C71924100 @default.
- W2383291301 hasConceptScore W2383291301C126322002 @default.
- W2383291301 hasConceptScore W2383291301C134018914 @default.
- W2383291301 hasConceptScore W2383291301C148762608 @default.
- W2383291301 hasConceptScore W2383291301C25498285 @default.
- W2383291301 hasConceptScore W2383291301C2777397205 @default.
- W2383291301 hasConceptScore W2383291301C2778541603 @default.
- W2383291301 hasConceptScore W2383291301C2780222073 @default.
- W2383291301 hasConceptScore W2383291301C42219234 @default.
- W2383291301 hasConceptScore W2383291301C541997718 @default.
- W2383291301 hasConceptScore W2383291301C71924100 @default.
- W2383291301 hasLocation W23832913011 @default.
- W2383291301 hasOpenAccess W2383291301 @default.
- W2383291301 hasPrimaryLocation W23832913011 @default.
- W2383291301 hasRelatedWork W1993999756 @default.
- W2383291301 hasRelatedWork W2015453126 @default.
- W2383291301 hasRelatedWork W2098282462 @default.
- W2383291301 hasRelatedWork W2330336890 @default.
- W2383291301 hasRelatedWork W2387811338 @default.
- W2383291301 hasRelatedWork W2409361708 @default.
- W2383291301 hasRelatedWork W2410387049 @default.
- W2383291301 hasRelatedWork W2461215239 @default.
- W2383291301 hasRelatedWork W2470963877 @default.
- W2383291301 hasRelatedWork W2495355668 @default.
- W2383291301 hasRelatedWork W3031513214 @default.
- W2383291301 hasRelatedWork W3141424571 @default.
- W2383291301 hasRelatedWork W3143166484 @default.
- W2383291301 hasRelatedWork W3143786785 @default.
- W2383291301 hasRelatedWork W3144902964 @default.
- W2383291301 hasRelatedWork W3148783766 @default.
- W2383291301 hasRelatedWork W3149805951 @default.
- W2383291301 hasRelatedWork W3151552026 @default.
- W2383291301 hasRelatedWork W3151647933 @default.
- W2383291301 hasRelatedWork W3029859147 @default.
- W2383291301 isParatext "false" @default.
- W2383291301 isRetracted "false" @default.
- W2383291301 magId "2383291301" @default.
- W2383291301 workType "article" @default.