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- W2383317861 abstract "Simulating natural cultivation conditions,to study on the elimination law of quinocetone residues in hybrid snakeheads( Channa maculata ♀ × Channa argus♂). 600 hybrid snakeheads were fed with feed mixed with75 mg /kg quinocetone for consecutive 60 d. Afterwards random sampling was done at 0. 25,0. 5,0. 75,1,1. 5,2,4,6,8,12,24,48,72,120,168,240,504 and 672 h. And 6 samples were collected at each collection point.Then LC- MS /MS was used to measure the residues of quinocetone in plasma,liver tissue and muscle tissue to study on the elimination law of quinocetone residues in hybrid snakeheads. The results indicated that quinocetone residues in plasma,liver tissue and muscle tissue reached the maximum concentration at 1. 5,1. 5 and 12 h respectively after stopping feeding. The peak concentration Cmaxof residues in plasma,liver and muscle were( 227. 0 ± 17. 71) μg /L,( 60.93 ±18.33) μg/kg and( 27.94 ±7.78) μg/kg,respectively. The elimination rates of quinocetone in hybrid snakeheads were different in different tissues with the highest in muscle,second in liver and lowest in plasma. The residue in muscle was lower than the detection limit at 504 h after the feeding. According to data from toxicologic study,safe tissue concentration( STC) of quinocetone in the edible tissue of aquatic products is 327 mg /kg. However,the results showed that,under the experimental conditions,the concentrations of quinocetone residues in plasma,liver and muscle tissue of hybrid snakeheads were lower than STC within 672 h of quinocetone withdrawal. [Chinese Fishery Quality and Standards,2014,4( 3) : 39- 45]" @default.
- W2383317861 created "2016-06-24" @default.
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- W2383317861 date "2014-01-01" @default.
- W2383317861 modified "2023-09-27" @default.
- W2383317861 title "The elimination law of quinocetone residues in hybrid snakeheads (Channa maculata♀ ×Channa argus♂)" @default.
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