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• W2383321373 abstract "Objective To investigate the alterations of serum thyroid hormone levels in senile patients with respiratory failure of chronic obstructive pulmonary disease COPD and its clinical significance. Methods Serum thyroid hormone levels were measured by chemiluminescence immunoassay in 38 senile COPD patients with respiratory failure in the acute exacerbation phase and in the stable phase and in 30 healthy elderly subjects as controls. Results The serum TT3 TT4 and FT3 levels were significantly lower in acute exacerbation phase of COPD patients(1.10±0.34)ng ml (89.56±22.84)μmol L (3.78±1.86)pg ml than those in stable phase of COPD(1.28±0.36)ng ml (102.78±24.12)μmol L (4.96±2.42)pg ml and in controls(1.36±0.38)ng ml(107.68±26.42)μmol L(5.38±2.56)pg mlt=2.1480,2.3175,2.2311,P0.05)and (t=2.9726,2.9853,2.9825,P0.01. There were no significant differences in serum TT3、TT4 and FT3 levels between COPD patients in the stable phase and healthy controls t=0.6280 0.7509 0.6533,均P0.05. The serum TT3 TT4 and FT3 levels were significantly lower in the fatal cases of COPD with respiratory failure(0.73±0.31)ng ml (65.42±20.83)μmol L(2.37±0.92)pg ml than those in survival cases(1.18±0.35)ng ml(93.86±22.92)μmol L (4.15±1.54)pg ml t=2.8626 2.75292.7225,P0.01. Conclusion The serum thyroid hormone levels were useful indicators for disease severity and prognosis of senile COPD patients with respiratory failure." @default.
• W2383321373 created "2016-06-24" @default.
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• W2383321373 date "2005-01-01" @default.
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• W2383321373 title "The alterations of serum thyroid hormone levels in senile patients with respiratory failure of chronic obstructive pulmonary disease" @default.
• W2383321373 hasPublicationYear "2005" @default.
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