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- W2383332145 abstract "Objective To observe the improvement of 6-minute walking distance of idiopathic pulmonary hypertension(IPAH) patients after four weeks' Bosentan treatment compared with baseline,and evaluate the WHO function classification,ultrasound cardiogram(UCG),clinical changes and non-invasive hemodynamic parameters change.Methods 26 cases of IPAH patients were treated with Bosentan for 4 weeks.Color doppler UCG was used to measure the changes of systolic pulmonary artery pressure(sPAP) before and after treatment.Results Bosentan can effectively improve the pulmonary artery pressure.Compared with pre-treatment,after treatment the indicators of 6MWD,WHO function classification,sPAP and UCG were significant differences(P 0.05 or P 0.01).The adverse reaction of Bosentan in the treatment of pulmonary hypertension was low.Conclusion Bosentan treatment can improve IPAH patients' athletic ability,improve cardiac function and difficulty breathing symptoms.Bosentan is a safe and effective drug in the treatment of IPAH." @default.
- W2383332145 created "2016-06-24" @default.
- W2383332145 creator A5053760788 @default.
- W2383332145 date "2012-01-01" @default.
- W2383332145 modified "2023-09-24" @default.
- W2383332145 title "Therapeutic efficacy and clinical analysis of Bosentan in the treatment of pulmonary hypertension" @default.
- W2383332145 hasPublicationYear "2012" @default.
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