Matches in SemOpenAlex for { <https://semopenalex.org/work/W2383344287> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W2383344287 abstract "Objective To find out the proteins interacting with tumor protein P53 inducible protein 11(PIG11) and get more information of the mechanism of PIG11 over-expresssion in human hepatoblastoma cell line(HepG2) cells. Methods The plasmid pLXSN was used to construct the human PIG11 gene retroviral vector,and PIG11 gene high expression HepG2 cell line was achieved after transfected.HepG2,pLXSN-HepG2,pLXSN-PIG11-HepG2 group were cultured,and cell apoptosis was analyzed by flow cytometer scans.PIG11 bingding proteins were recoverd by Co-immunoprecipitation,protein identification was performed by Mass spectrometry,peptide sequence tags were analyzed by Mascot database.Results The apopotosis rate of HepG2-pLXSN-PIG11 was higher than that of HepG2-pLXSN and the control HepG2.Mass spectrometry analysis allowed the identification of 11 PIG11 interacting proteins: Hsp60,KSRP,Brain abundant membrane attached Signal protein 1(BASP1),Dermcidin(DCD/PIF),Y-chromosome RNA recognition Motif protein,Carbonate dehydratase,ALB protein,Vimentin,Alpha-tubulin,Tubulin 5-bete and Actin. Conclusion The findings suggest that over-expression of PIG11 induce HepG2 cells apoptosis.11 PIG11 interacting proteins were identified,which can provide us a clue on further studying the function of PIG11." @default.
- W2383344287 created "2016-06-24" @default.
- W2383344287 creator A5032564609 @default.
- W2383344287 date "2009-01-01" @default.
- W2383344287 modified "2023-09-24" @default.
- W2383344287 title "Initial Separation and Identification of the PIG11 Interacting Proteins in Human Hepatocellular Carcinoma HepG2 Cells" @default.
- W2383344287 hasPublicationYear "2009" @default.
- W2383344287 type Work @default.
- W2383344287 sameAs 2383344287 @default.
- W2383344287 citedByCount "0" @default.
- W2383344287 crossrefType "journal-article" @default.
- W2383344287 hasAuthorship W2383344287A5032564609 @default.
- W2383344287 hasConcept C104317684 @default.
- W2383344287 hasConcept C147447768 @default.
- W2383344287 hasConcept C153911025 @default.
- W2383344287 hasConcept C185592680 @default.
- W2383344287 hasConcept C203014093 @default.
- W2383344287 hasConcept C204232928 @default.
- W2383344287 hasConcept C54009773 @default.
- W2383344287 hasConcept C54355233 @default.
- W2383344287 hasConcept C55493867 @default.
- W2383344287 hasConcept C81885089 @default.
- W2383344287 hasConcept C86803240 @default.
- W2383344287 hasConceptScore W2383344287C104317684 @default.
- W2383344287 hasConceptScore W2383344287C147447768 @default.
- W2383344287 hasConceptScore W2383344287C153911025 @default.
- W2383344287 hasConceptScore W2383344287C185592680 @default.
- W2383344287 hasConceptScore W2383344287C203014093 @default.
- W2383344287 hasConceptScore W2383344287C204232928 @default.
- W2383344287 hasConceptScore W2383344287C54009773 @default.
- W2383344287 hasConceptScore W2383344287C54355233 @default.
- W2383344287 hasConceptScore W2383344287C55493867 @default.
- W2383344287 hasConceptScore W2383344287C81885089 @default.
- W2383344287 hasConceptScore W2383344287C86803240 @default.
- W2383344287 hasLocation W23833442871 @default.
- W2383344287 hasOpenAccess W2383344287 @default.
- W2383344287 hasPrimaryLocation W23833442871 @default.
- W2383344287 hasRelatedWork W1542423222 @default.
- W2383344287 hasRelatedWork W1995989104 @default.
- W2383344287 hasRelatedWork W2005453501 @default.
- W2383344287 hasRelatedWork W2023099665 @default.
- W2383344287 hasRelatedWork W2050054702 @default.
- W2383344287 hasRelatedWork W2054376792 @default.
- W2383344287 hasRelatedWork W2055185192 @default.
- W2383344287 hasRelatedWork W2085523227 @default.
- W2383344287 hasRelatedWork W2087493485 @default.
- W2383344287 hasRelatedWork W2092670341 @default.
- W2383344287 hasRelatedWork W2357354294 @default.
- W2383344287 hasRelatedWork W2380822515 @default.
- W2383344287 hasRelatedWork W2412130460 @default.
- W2383344287 hasRelatedWork W2415395392 @default.
- W2383344287 hasRelatedWork W2417704324 @default.
- W2383344287 hasRelatedWork W2791269776 @default.
- W2383344287 hasRelatedWork W3016806887 @default.
- W2383344287 hasRelatedWork W3149289964 @default.
- W2383344287 hasRelatedWork W3149649317 @default.
- W2383344287 hasRelatedWork W3151907711 @default.
- W2383344287 isParatext "false" @default.
- W2383344287 isRetracted "false" @default.
- W2383344287 magId "2383344287" @default.
- W2383344287 workType "article" @default.