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- W2383364504 abstract "To investigate the serum levels of VEGF and MMP-9 and the relationship between these proteins and colorectal tumor differentiation, Duckes stage. Methods Serum levels of VEGF and MMP-9 in 48 patients with colorectal carcinoma were measured by ELISA. Results Serum levels of VEGF(665.8±232.8ng/l) and MMP-9(532.7±208.9ug/l) were significantly higher in the cancer patients than those of control(391.6±135.2;317.8±132.2)(p0.01). The levels were associated with tumor differentiation and Duckes stage. Patients with poor differentiated and Duckes C or D stage tumors had significantly higher levels of VEGF and MMP-9 than those of patients with well differentiated and Duckes A or B stage tumors(P0.01). Conclusion Elevated VEGF and MMP-9 serum levels are associated with tumor differentiation ,invasion,metastasis,which may serve as markers of tumor progression and poor prognosis." @default.
- W2383364504 created "2016-06-24" @default.
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- W2383364504 date "2005-01-01" @default.
- W2383364504 modified "2023-09-24" @default.
- W2383364504 title "Serum VEGF amd MMP-9 Levels in Patients with Colorectal Carcinoma and Their Significance" @default.
- W2383364504 hasPublicationYear "2005" @default.
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