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- W2383379244 abstract "Objective To study the improving effects of Tianzhusan( TZS) on dementia disease-like mice induced with D-galactose. Methods The model of dementia was induced by subcutaneously injecting D-galactose in the nape of the mice. After 14 days,the different doess of TZS were orally administered for preventive treatment. The therapeutic effects of TZS were observed by detecting the changes of learning and memory ability with the eight-arm maze and the hippocampal structure and neural cells of model mice with H. E. and Nissl's method staining. Results TZS can decrease the RME and WME of model mice( P 0. 05). TZS can also alleviate the neuronal degeneration and Nissl's bodies loss in hippocampal CA1 of model mice induced by brain aging.Conclusion TZS can improve the learning and memory abilities and protect the nerve cells in hippocampus of dementia disease-like mice induced with D-galactose." @default.
- W2383379244 created "2016-06-24" @default.
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- W2383379244 date "2015-01-01" @default.
- W2383379244 modified "2023-09-26" @default.
- W2383379244 title "Study on the Effects of Tianzhusan on Improving Learning and Memory Abilities of Dementia Disease-like Mice induced with D-Galactose" @default.
- W2383379244 hasPublicationYear "2015" @default.
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