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- W2383382080 abstract "Aim: To explore the pathologic and pathophysiologic mechanism following traumatic brain injury at moleculor level, and to provide some theoretical guidance for the correct clinical evaluation of the patients' traumatic condition and for prognosis. Methods: C fos gene expression in the local neural tissue was studied in 31 cases of brain injury and in 12 autopsy cases of sudden death without brain injury, adopting immunohistochemical techniques and the colorous multi function image analysis system (CMIAS). Results: In all the brain injury cases, there was a dramatic increase in C fos gene expression at the site of injury and in surrounding tissues and furthermore followed by a specific time course, compared with that in autopsy cases. Significantly higher level of C fos expression was found in the injured neural tissue of the GCS8 group than the GCS≥8 group, and also in that of the non survivors within two weeks post trauma than the survivors. Conclusion: It suggests that C fos gene expression can, to an extent, act as one of the clinical indicators of extent of brain injury and prognosis." @default.
- W2383382080 created "2016-06-24" @default.
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- W2383382080 date "1997-01-01" @default.
- W2383382080 modified "2023-09-26" @default.
- W2383382080 title "C fos Gene Expression in Local Cerebral Tissue following Brain Injury" @default.
- W2383382080 hasPublicationYear "1997" @default.
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