Matches in SemOpenAlex for { <https://semopenalex.org/work/W2383437504> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2383437504 endingPage "50" @default.
- W2383437504 startingPage "646" @default.
- W2383437504 abstract "Increased formation of advanced glycation end-products (AGEs) is occurred in hyperglyceamia and diabetes, leading to oxidative stress and progression of diabetic vascular diseases. Glucose-6-phosphate dehydrogenase (G6PD), the principal source of NADPH, serves as an antioxidant enzyme to modulate the redox milieu. Deficiency of G6PD activity is associated with increased endothelial cell oxidative stress. Current study is designed to investigate the effects of AGEs on G6PD activity and expression in human umbilical vein endothelial cells. Treatment of AGE-modified bovine serum albumin (AGE-BSA, 100 µg/mL, 24 h), but not native BSA, to human umbilical vein endothelial cells increased ROS generation by (48.89 ± 5.28)%. G6PD activity was decreased by AGE-BSA treatment by (61.25 ± 11.2)%. The expression of G6PD at mRNA and protein levels was also decreased by AGE-BSA treatment by (27.92 ± 6.73)% and (23.72 ± 2.44)%, respectively. These results suggest that AGEs could result in G6PD deficiency in human umbilical vein endothelial cells by inhibiting the expression of G6PD at mRNA and protein levels and G6PD activity." @default.
- W2383437504 created "2016-06-24" @default.
- W2383437504 creator A5049432845 @default.
- W2383437504 creator A5086664284 @default.
- W2383437504 date "2012-12-25" @default.
- W2383437504 modified "2023-10-18" @default.
- W2383437504 title "Advanced glycation end products inhibit glucose-6-phosphate dehydrogenase activity and expression in human umbilical vein endothelial cells." @default.
- W2383437504 cites W1493971026 @default.
- W2383437504 cites W1523040131 @default.
- W2383437504 cites W1992462947 @default.
- W2383437504 cites W2010151178 @default.
- W2383437504 cites W2031526143 @default.
- W2383437504 cites W2032670192 @default.
- W2383437504 cites W2059318458 @default.
- W2383437504 cites W2091916032 @default.
- W2383437504 cites W2093792755 @default.
- W2383437504 cites W2098616484 @default.
- W2383437504 cites W2103528436 @default.
- W2383437504 cites W2108762011 @default.
- W2383437504 cites W2127764309 @default.
- W2383437504 cites W53554225 @default.
- W2383437504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23258327" @default.
- W2383437504 hasPublicationYear "2012" @default.
- W2383437504 type Work @default.
- W2383437504 sameAs 2383437504 @default.
- W2383437504 citedByCount "2" @default.
- W2383437504 countsByYear W23834375042015 @default.
- W2383437504 countsByYear W23834375042022 @default.
- W2383437504 crossrefType "journal-article" @default.
- W2383437504 hasAuthorship W2383437504A5049432845 @default.
- W2383437504 hasAuthorship W2383437504A5086664284 @default.
- W2383437504 hasConcept C123012128 @default.
- W2383437504 hasConcept C126322002 @default.
- W2383437504 hasConcept C134018914 @default.
- W2383437504 hasConcept C147990577 @default.
- W2383437504 hasConcept C16685009 @default.
- W2383437504 hasConcept C181199279 @default.
- W2383437504 hasConcept C185592680 @default.
- W2383437504 hasConcept C202751555 @default.
- W2383437504 hasConcept C2776151105 @default.
- W2383437504 hasConcept C2776317432 @default.
- W2383437504 hasConcept C2776992346 @default.
- W2383437504 hasConcept C2776997535 @default.
- W2383437504 hasConcept C2777411675 @default.
- W2383437504 hasConcept C2777834122 @default.
- W2383437504 hasConcept C2778004101 @default.
- W2383437504 hasConcept C2780196906 @default.
- W2383437504 hasConcept C55493867 @default.
- W2383437504 hasConcept C555293320 @default.
- W2383437504 hasConcept C71924100 @default.
- W2383437504 hasConcept C86803240 @default.
- W2383437504 hasConcept C86807702 @default.
- W2383437504 hasConceptScore W2383437504C123012128 @default.
- W2383437504 hasConceptScore W2383437504C126322002 @default.
- W2383437504 hasConceptScore W2383437504C134018914 @default.
- W2383437504 hasConceptScore W2383437504C147990577 @default.
- W2383437504 hasConceptScore W2383437504C16685009 @default.
- W2383437504 hasConceptScore W2383437504C181199279 @default.
- W2383437504 hasConceptScore W2383437504C185592680 @default.
- W2383437504 hasConceptScore W2383437504C202751555 @default.
- W2383437504 hasConceptScore W2383437504C2776151105 @default.
- W2383437504 hasConceptScore W2383437504C2776317432 @default.
- W2383437504 hasConceptScore W2383437504C2776992346 @default.
- W2383437504 hasConceptScore W2383437504C2776997535 @default.
- W2383437504 hasConceptScore W2383437504C2777411675 @default.
- W2383437504 hasConceptScore W2383437504C2777834122 @default.
- W2383437504 hasConceptScore W2383437504C2778004101 @default.
- W2383437504 hasConceptScore W2383437504C2780196906 @default.
- W2383437504 hasConceptScore W2383437504C55493867 @default.
- W2383437504 hasConceptScore W2383437504C555293320 @default.
- W2383437504 hasConceptScore W2383437504C71924100 @default.
- W2383437504 hasConceptScore W2383437504C86803240 @default.
- W2383437504 hasConceptScore W2383437504C86807702 @default.
- W2383437504 hasIssue "6" @default.
- W2383437504 hasLocation W23834375041 @default.
- W2383437504 hasOpenAccess W2383437504 @default.
- W2383437504 hasPrimaryLocation W23834375041 @default.
- W2383437504 hasRelatedWork W151770906 @default.
- W2383437504 hasRelatedWork W2005653939 @default.
- W2383437504 hasRelatedWork W2014484768 @default.
- W2383437504 hasRelatedWork W2242045527 @default.
- W2383437504 hasRelatedWork W2335890154 @default.
- W2383437504 hasRelatedWork W2383437504 @default.
- W2383437504 hasRelatedWork W2611947667 @default.
- W2383437504 hasRelatedWork W2905568885 @default.
- W2383437504 hasRelatedWork W3147934552 @default.
- W2383437504 hasRelatedWork W3179822928 @default.
- W2383437504 hasVolume "64" @default.
- W2383437504 isParatext "false" @default.
- W2383437504 isRetracted "false" @default.
- W2383437504 magId "2383437504" @default.
- W2383437504 workType "article" @default.