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- W2383444763 abstract "Objective To investigate the role of biventricular pacing on reverse remodeling and improvement of cardiac function Methods Twenty patients [ mean age (63 ±13 )years, 14 males] with NYHA class III to IV heart failure, ejection fraction40% and QRS duration140ms were recruited for biventricular pacing therapy Serial assessment was performed before and up to 3 months after pacing, and repeated when pacing was withheld up to 4 weeks Results There was significant improvement of ejection fraction, cardiac output and left ventricular filling time; and decrease in mitral regurgitation, left ventricular end diastolic[ (196±69)ml vs (159±64)ml, P 0 01] and end systolic volumes [(155±71)ml vs (117±56)ml, P 0 01] after pacing for 3 months Six minute hall walk distance [(332±89)m vs (372±76)m , P 0 05] and quality of life score were also improved These benefits were pacing dependent as withholding the pacing resulted in varying speeds in the loss of cardiac functional and structural improvements Conclusions Synchronous biventricular pacing reverses left ventritricular remodeling and improves cardiac function in patients with NYHA class III to IV heart failure and electrocardiographic evidence of ventricular conduction delay" @default.
- W2383444763 created "2016-06-24" @default.
- W2383444763 creator A5077574341 @default.
- W2383444763 date "2002-01-01" @default.
- W2383444763 modified "2023-09-26" @default.
- W2383444763 title "Short-term assessment of the therapeutic efficacy of biventricular pacing in patients with congestive heart failure" @default.
- W2383444763 hasPublicationYear "2002" @default.
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