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- W2383465498 abstract "Objective To study whether in postmenopansal women levels of serum vitamin B12 and serum folate are related to bone mineral density(BMD). Methods (1) Serum vitamin 12 levels and serum folate levels were measured using chemiluminescence (DPC corporation). (2)BGP and PTH levels were measured by chemiluminescence (equipment is Roche E170).(3)ALP,Ca and P were measured by automated biochemistry techniques.(4)BMD was measured using dual energy X-ray analysis(GE PRODIGY Inc.) at the lumbar spine(L_1-L_4) and at the left hip(total hip,trochanter,Ward's area and femoral neck). Results (1) Osteoporotic women had lower values of serum vitamin B12osteoporosis group (512.55±209.85) pg/ml,osteopenia group (551.29±237.71) pg/ml and normal group (565.71±189.03) pg/ml. (2) Osteoporotic women had lower values of serum folate osteoporosis group (11.27±6.04) pg/ml than osteopenia group (13.18±6.14) pg/ml and normal group (11.9±3.73) pg/ml. (3) Low vitamin B12 level and low BMD value at each of the hip sites and for total hip are of positive correlation(total hip r=0.25,P0.01,trochanter r=0.239, P0.05, shaft of femur r=0.257, P0.01 and femoral neck r=0.212,P0.05). Low vitamin B12 level and low BMD value at lumbar spine(L_1-L_4) are of no correlation(r=0.141,P0.05). Low folate levels and low BMD value at each of the hip sites and for total hip are of no correlation(total hip r=0.005,P0.05,trochanter r=-0.021, P0.05, shaft of femur r=0.017, P0.05and femoral neck r=0.021, P0.05). Low folate levels and low BMD value at lumbar spine(L_1-L_4) are of no correlation(r=0.078,P0.05).Conclusions Serum vitamin B12 deficiency may be an important risk factor for osteoporosis. Serum folate deficiency isn't a risk factor for osteoporosis." @default.
- W2383465498 created "2016-06-24" @default.
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- W2383465498 date "2007-01-01" @default.
- W2383465498 modified "2023-09-23" @default.
- W2383465498 title "Relation of serum vitamin B12 and serum folate to bone mineral density in postmenopansal women" @default.
- W2383465498 hasPublicationYear "2007" @default.
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