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- W2383554906 abstract "Objective To observe the expression of beta-catenin protein in cultured bone marrow stromal cells (BMSC) of ovariectomized rats. Methods Eighteen female Sprague Dawley rats (3 months old) were randomly divided into 2 groups. The ovariectomy group received ovariectomy in both sides. The matched Sham group received false surgical operation. After 14 weeks, the BMSC were freshly isolated from bone marrow of left femurs and cultured by static adherent culture for 9 days. Their right femurs were processed calculation of BMD in the bone density machine. The expression of beta-catenin protein in cultured BMSC was investigated by indirect immunofluoresence. Results BMD of the femur trabecular reduced significantly in the ovariectomy group compared with the Sham-operation group. Compared with the Sham group, the expression of beta-catenin protein in nuclear of cultured BMSC decreased in the ovariectomized group. Conclusion The expression change of beta-catenin protein in cultured BMSC may be related to the development of post-menopausal osteoporosis." @default.
- W2383554906 created "2016-06-24" @default.
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- W2383554906 date "2008-01-01" @default.
- W2383554906 modified "2023-09-23" @default.
- W2383554906 title "Observation of the expression of beta-catenin protein in cultured bone marrow stromal cells of ovariectomized rats" @default.
- W2383554906 hasPublicationYear "2008" @default.
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