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- W2383558265 abstract "Objective: To investigate the inhibitive effects of static magnetic fields(SMF) with 300 mT intensity on diabetes-induced epidermal wound healing in rats,and to provide the important experimental basis for the clinical application of static magnetic fields.Methods: Eight-week old female Sprague-Dawley(SD) rats with 220 ± 20 g body weight were given single intravenous administration of streptozotocin(STZ) at a dose of 50 mg/kg versus body weight.Animals with fasting blood glucose concentration higher than 16.7 mmol/L were employed in the following experiment.One open circular wound with 2 cm diameter in the dorsum was generated on either normal or diabetic mice and then covered with sterile gauzes 1 day post surgery.Sixteen normal mice were used as the Control group,and 32 diabetic mice were randomly divided into Diabetes and SMF treatment group.The rats in SMF treatment group were exposed to SMF by gluing one magnetic disk with 300 mT intensity.On days 6,13 and 20,four rats in each group were euthanized,and the gross wound area and the tensile strength of the soft tissue were respectively qualified.Results: Compared with that in the Diabetes group,diabetic rats under SMF exposure demonstrated significantly accelerated process in the epidermal wound healing(P0.05),as well as dramatically higher tissue tensile strength(P0.05) at day 6,13 and 20.The wound recovery process of diabetic rats under SMF exposure was close to that of rats in the control group.Conclusion: SMF with 300 mT has the capacity of remarkably accelerating the diabetic wound healing process in rats.SMF treatment,as an economic,easy and convenient method,possesses bright application potential in clinics for promoting diabetic wound healing." @default.
- W2383558265 created "2016-06-24" @default.
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- W2383558265 date "2013-01-01" @default.
- W2383558265 modified "2023-09-26" @default.
- W2383558265 title "Effects of 300 mT Static Magnetic Fields on Diabetic Wound Healing in Rats" @default.
- W2383558265 hasPublicationYear "2013" @default.
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