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- W2383559956 abstract "Objective To evaluate efficacy of the combined treatment for severe intrahepatic cholestasis of pregnancy(ICP).Methods Sixty severe symptomatic patients with intrahepatic cholestasis of pregnancy were randomized to receive either combined treatment:SAMe+phosphatidylcholine+Dexamtehason daily(n=30);or single SAMe daily(n=30),for 7 days.Results After combined treatment,there were significant decreases on the degree of pruritus and the maternal blood level of biochemical parameters such as TBA,DB/TB,ALT/AST(P0.01);compared with single treated group,the pregnancy period was significant prolonged;the rate of vagina delivery and the weight of newborns were increased,preterm delivery and RDS were great decreased(P0.01).However the fetal distress,meconium passage and newborn asphyxia rate had no statistical difference between the two groups(P0.05).Conclusion The combined treatment is more effective than the single SAMe for severe intrahepatic cholestasis of pregnancy." @default.
- W2383559956 created "2016-06-24" @default.
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- W2383559956 date "2007-01-01" @default.
- W2383559956 modified "2023-09-26" @default.
- W2383559956 title "Combined treatment for severe intrahepatic cholestasis of pregnancy:analysis of 30 cases" @default.
- W2383559956 hasPublicationYear "2007" @default.
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