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- W2383581498 abstract "The recombinant Chinese Hamster Ovary cell-CHO-C2, ,which could express and excrete HBsAg in high titer,was cultured in 10L roller bottles with both domestic and foreign medium of Delbeco's Modified Eagle's Medium (DMEM).The comparative result showed that the cell growth as well as HBsAg titer was not significantly different with these two media. The amount and the recovery rate of precipitate by the approach with domestic DMEM was higher than that of foreign medium trespectively, the final recovery rate of products by the acquisition with domestic medium was not less than that of foreign DMEM. The purified HBsAg products could meet all of the Requirements for Recombinant Hepatatis B Vaccine manufature and Quality Control. It was concluded that it was reliable to use domestic DMEM instead of foreign medium in the production." @default.
- W2383581498 created "2016-06-24" @default.
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- W2383581498 date "1999-01-01" @default.
- W2383581498 modified "2023-09-25" @default.
- W2383581498 title "QUALITY EVALUATION OF CHO-C_(28) RECOMBINANT CELLS CULTURED IN DOMESTIC AND FOREIGN OF DMEM" @default.
- W2383581498 hasPublicationYear "1999" @default.
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