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- W2383669490 abstract "[Objective] To compare the effect of preinjecting xafon on patient-controlled epidural analgesia for postoperative pain relief after hysterectomy. [Methods] 60 ASA I～II patients undergoing hysterectomy who were matched in age, weight, and duration of surgical procedure, were randomly allocated to one of the three treatment groups 20 in each: group I injected saline 10 mL before skin incision, group II injected xafon to the end surgery, and group III injected xafon before skin incision. Patient-controlled epidural analgesia (0.125% Bupivocaine and 2 μg/mL fentanyl) was given for postoperative pain relief in all group (5 mL bolus followed by 2 mL/h infusion, PCA dose: 2 mL, lock out time: 15 min) Postoperative pain intensity at rest and during movement was assessed on a Visual analogue scale (VAS) by a blinded observer for 48 h after surgery. Analgesic requirements and side effects were compared among the three groups. [Results] In the first 24 h after surgery, the VAS score at rest reported by the patient in group I was significantly higher than that in group II (P 0.05) and that in group III (P 0.01), while the VAS score during coughing in group I was higher than that in group II and that in group III (P 1.01). Analgesic requirements in the first 24 h were (99±15) mL in group I, (83±8) mL in group II, and (78±9) mL in group III, without significant difference among the groups. However, the analgesic requirement in the second 24 h was (81±10) mL in group I, much more than that in group II (P 0.05) and in group III (P 0.01). The incidence of nausea, was significantly higher in group I than in group III. [Conclusion] The preoperative administration xafon before skin incision on patient-controlled epidural analgesia for postoperative pain relief compared with saline administration. Improves the postoperative pain management and reduces postoperative analgesic consumption and side effects." @default.
- W2383669490 created "2016-06-24" @default.
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- W2383669490 date "2006-01-01" @default.
- W2383669490 modified "2023-09-24" @default.
- W2383669490 title "Effects of preinjecting xafon on patient-controlled epidural analgesia for postoperative pain relief following hysterectomy" @default.
- W2383669490 hasPublicationYear "2006" @default.
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