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- W2383813564 abstract "AIM: To investigate the clinical effect of Maiditong for injection(Herba Erigerontis) on coagulative and fibrionlytic system in diabetic nephropathy(DN). METHODS: 59 patients definitely diagnosed as diabetes type 2 DN were randomly divided into treatment and control groups.The treatment group were treated with Maiditong for injection,and the control group were treated with of Compound Danshen Injection.The 24 h proteinuria and vWF:Ag、Fbg、PF_(1+2)、FPA、D-dimer、AT-Ⅲ:A、tPA、PAI-1、PIC、PLG were tested before and after the therapies. RESULTS: After one therapy course(2 weeks),in the treatment group the 24 h proteinuria decreased obviously(P(0.05)) and their renal function was obviously improved(P0.05).The changes in the treatment group were more significant than that in the control group(P0.05).After the therapies,in the treatmnet group the level of vWF:Ag、Fbg、PF_(1+2)、FPA、D-dimer、PAI-1 decreased significantly(P0.05 or P0.01) but the level of AT-Ⅲ:A、PLG、tPA、PIC increased significantly(P0.05 or P0.01).All these changes were more obvious than that in the control group(P0.05 or P0.01). CONCLUSION: Maiditong for injection can significantly meliorate hypercoagulable state in diabetes type 2 DN,reduce the urinary protein and delay the processing of renal failure." @default.
- W2383813564 created "2016-06-24" @default.
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- W2383813564 date "2007-01-01" @default.
- W2383813564 modified "2023-09-24" @default.
- W2383813564 title "Effect of Maiditong for injection on coagulative and fibrionlytic system in diabetic nephropathy" @default.
- W2383813564 hasPublicationYear "2007" @default.
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