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- W2383822264 abstract "[Objective]To investigate relationships between NO,NOS and senescence by simultaneous determination of NO content and NOS activity.[Methods]Nuchal injection of D-galactose was administered continuously for 42 days to produce subcute senescence models,whereas normal saline for the control group.The NO content in in cerebral cortex was determined by nitrate reduetase method and the NOS activity was detected by chemical colorimetry.[Results]Contents of NO in cerebrum and cerebellum in the model group significantly increased compared with the control group;NOS activity in cerebrum in the model group was more intense than that in the control group.[Conclusion]D-galactose-induced increases of NO content and NOS activity are closely correlated with the development of senescence.Changes of NO content and NOS activity can be a sensitive index of neural aging." @default.
- W2383822264 created "2016-06-24" @default.
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- W2383822264 date "2007-01-01" @default.
- W2383822264 modified "2023-09-27" @default.
- W2383822264 title "CHANGES OF NITRIC OXIDE(NO) CONTENT AND NITRIC OXIDE SYNTHETASE(NOS) ACTIVITY IN CEREBRAL CORTEX OF MICE WITH SUBACUTE SENESCENCE" @default.
- W2383822264 hasPublicationYear "2007" @default.
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