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- W2383829916 abstract "Objective To investigate the gene expression of transforming growth factor-β1 (TGF-β1),TGF-β3,and their two receptors (TBRⅠand TBRⅡ) in fetal and children skin.Methods The gene expression of TGF-β1,TGF-β3,TBRⅠand TBRⅡ in skin at different developmental stages was detected by using reverse transcription-polymerase chain reaction (RT-PCR) assay.Results In early gestational fetal skin,the gene expression of TGF-β1,TBRⅠand TBRⅡ was weaker.Along with the increment in gestational age,the gene expression of these 3 genes was elevated.In children skin,the expression levels of these 3 genes were 1.3,1.3,1.2 folds of early gestational skin,respectively.In marked contrast,the content of TGF-β3 gene transcript was higher in early gestational skin than in late gestational and children skin (P0.05).Conclusion The relative lack of gene expression of TGF-β1,TBRⅠand TBRⅡ and increment of TGF-β3 gene expression in skin of younger fetuses might be involved in fetal scarless healing." @default.
- W2383829916 created "2016-06-24" @default.
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- W2383829916 date "2003-01-01" @default.
- W2383829916 modified "2023-09-24" @default.
- W2383829916 title "Gene expression of transforming growth factor-β1,β3 in fetal and children skin" @default.
- W2383829916 hasPublicationYear "2003" @default.
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