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- W2383867099 abstract "Objective To observe the syphilis serology results and outcomes of newborns from pregnant women with syphilis,and to evaluate the effects of neonatal serum IgM antibody protein immunoblot experiment in the earlystage diagnosis. Methods 385 cases of pregnant syphilis production of newborn from 2010 to 2011 in Fujian Provincial Maternity and Child Care Center were included into this study. All these patients were followup and were checked RPR / TPPA after born. And the positiveresult of the newborn were used to check TPIgMWB. The newborn's serum with positive outcome during the 1st month,the 3rd month and 6th month were analyzed. The experiment was used to understand the false positive cases of infants with congenital syphilis,and to evaluate of neonatal serum IgM antibody protein immunoblot experiment in the earlystage diagnosis. Results Among 385 cases of pregnancy complicated syphilis patients' newborns,238 cases shown positive results in RPR and TPPA test and 19 of them was positive in TPIgMWB test. 76 cases were followup and all the 76 cases had negative results in TPIgMWB test,refused to accept preventive treatment. In six months,73 cases had negative results in RPRtest and 64 cases had negative results in TPPAtest. The cases with negative results in both TPIgMWB test and RPR test were similar. The result had no statistical difference( χ2= 1. 36,P 0. 05). Conclusion There is lack of sufficient evidence to diagnose congenital syphilis only according to positive results in RPR and TPPA tests. Newborn serum IgM antibody protein immunoblot experiment test will improve the diagnostic accuracy of congenital syphilis." @default.
- W2383867099 created "2016-06-24" @default.
- W2383867099 creator A5071296152 @default.
- W2383867099 date "2013-01-01" @default.
- W2383867099 modified "2023-09-28" @default.
- W2383867099 title "Serology prognosis analysis of 385 cases of pregnancy complicated syphilis patients' newborns" @default.
- W2383867099 hasPublicationYear "2013" @default.
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