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- W2383925925 abstract "Objective To observe the effect of probucol on the level of MMP-9 in acute stage of cerebral infarction.Methods Using a random and single blind control test ,82 patients with cerebral infarction in acute stage were randomed into probucol group(n=42) and control group(n=40).With the method of ELISA, the levels of MMP-9in serum were measured before and after therapy.Results(1) The serum MMP-9 levels of Probucol group pre-treatment was 398.67±84.92ng/ml, two weeks after treatment 173.80±55.68ng/ml, signifi cantly lower than that before treatment(P0.05);The serum MMP-9 levels of control group pre-treatment serum levels was 401.12±62.56ng/ml, two weeks after treatment 352.98±89.65ng/ml, no signifi cant difference between before and after treatment(P0.05);(2) At the end of two weeks after treatment, the serum MMP-9levels of robucol group was signifi cantly lower than that of control group(P0.05).Conclusion Probucol can reduce the level of MMP-9 in acute stage of cerebra linfarction, thus may relieve the ischemic brain injury." @default.
- W2383925925 created "2016-06-24" @default.
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- W2383925925 date "2009-01-01" @default.
- W2383925925 modified "2023-09-25" @default.
- W2383925925 title "Inhibition Effect of Probucol on the Level of MMP-9 in Acute Stage of Cerebral Infarction" @default.
- W2383925925 hasPublicationYear "2009" @default.
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