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- W2383963002 abstract "Whether tachyplesin-I could induce resistance in Escherichia coli by UV mutagenesis and determination of the susceptibility testing for antibiotic in induction resistant strains were explored.Firstly,after Escherichia coli ATCC25922 and JM109 wrer treated by UV mutagenesis techniques,the resistance to tachyplesin-I strains through tachyplesin concentration gradient flat was selected,and taking the corresponding non-mutagenesis strains as a control.Subsequently,the induction resistant strains were performed by continuous passage in sub-inhibitory concentration of tachyplesin-I and the susceptibility were tested for antibiotics(Benzathine Benzylpenicillin and levofloxacin hydrochloride).The experimental results indicated that three induction strains for Escherichia coli ATCC25922 with low resistance to tachyplesin-I were induced and isolated by UV mutagenesis and sub-inhibitory concentration continuous induction methods.Determination of susceptibility testing for antibiotic in the selected resistant strains to tachyplesin-I indicated that there was a notable increase in resistance to Benzathine Benzylpenicillin and no resistance to levofloxacin hydrochloride.Tachyplesin-I didn't induce resistance in JM109 by UV mutagenesis,and part of the induction strains become more susceptible to Tachyplesin-I." @default.
- W2383963002 created "2016-06-24" @default.
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- W2383963002 date "2013-01-01" @default.
- W2383963002 modified "2023-09-26" @default.
- W2383963002 title "Study on Escherichia coli resistance to Tachyplesin-I induced by UV mutagenesis" @default.
- W2383963002 hasPublicationYear "2013" @default.
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