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- W2383968712 abstract "To explore the prognostic markers in osteosarcoma.Expressions of p53, c-myc, bcl-2 and apoptosis index (AI) in 28 osteosarcoma specimens were detected by ABC immunohistochemistry and terminal deoxynucleotidyl transferase (TdT)-mediated dUTP-digoxigenin nick end labelling (TUNEL). The relationship between gene expression and apoptosis, and their correlations with pathologic classification and prognostic factors were analyzed.There was negative correlation between the expressions of p53, c-myc, bcl-2 protein and AI, which was closely related to the long term survival of patients but was not related to pathologic types of the tumor.The expressions of p53, c-myc, bcl-2 protein and AI can be used as an index for predicting the progression and prognosis of osteosarcoma." @default.
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- W2383968712 date "2004-11-01" @default.
- W2383968712 modified "2023-09-24" @default.
- W2383968712 title "[Apoptosis-related gene expression and its clinical significance of human osteosarcoma]." @default.
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