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- W2383973504 abstract "A HPLC method was established for the simultaneous determination of phenobarbital, lamotrigine, oxcarbazepine and monohydroxycarbazepine in human plasma. The analytes were extracted by protein precipitation, using chlorzoxazone as internal standard. A XDB-C18 column was used with the mobile phase of methanol-0.1 % triflouroacetic acid (38:62). Phenobarbital and monohydroxycarbazepine were detected at the wavelength of 215nm, while lamotrigine and oxcarbazepine at 240 nm. The calibration curves were linear in the ranges of 5 - 100, 1 - 50, 0.5 - 50 and 2 - 100μg/ml, respectively. The average recoveries were 101.3%, 100.7%, 96.7% and 101.5%, respectively." @default.
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- W2383973504 date "2006-01-01" @default.
- W2383973504 modified "2023-09-25" @default.
- W2383973504 title "Determination of Phenobarbital, Lamotrigine, Oxcarbazepine and Monohydroxycarbazepine in Human Plasma by HPLC" @default.
- W2383973504 hasPublicationYear "2006" @default.
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