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- W2384001724 abstract "OBJECTIVE To explore the clinical effects of intrathecal infection with ceftazidime to reduce the incidence rate of surgical intracranial infection.METHODS A total of 183 neurosurgical patients who accepted craniotomy and with surgical potential intracranial infection were divided into groups A or B.All 183 patients were primarily treated with ceftazidime iv,but only 91 cases of group A were then treated with ceftazidime by intrathecal injection.From every group were taken 10 cases,and the drug concentrations of ceftazidime in the drainaged CSF from wound surfaces of them were detected.RESULTS Only 8 patients of group A developed into intracranial infection,but 26 cases in the group B.The drug concentration of ceftazidime in the drainaged CSF from group A only was 1.2 μg/ml and beyond the 1.0 μg/ml MIC.CONCLUSIONS It is effective to prevent the occurring of intracranial infection by intrathecal injection with ceftazidime on potential cases which accepted craniotomy." @default.
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- W2384001724 date "2009-01-01" @default.
- W2384001724 modified "2023-09-27" @default.
- W2384001724 title "Effect of Intrathecal Injection with Ceftazidime on Surgical Potential Intracranial Infection" @default.
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