Matches in SemOpenAlex for { <https://semopenalex.org/work/W2384009162> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W2384009162 abstract "Objective To detect single nucleotide polymorphisms(SNPs) of two pharmacokinetics related genes in three pancreatic cancer cell lines in order to provide references for prediction clinical efficacy and toxicity of fluorouracil.Methods PANC-1,CFPAC and SW1990 cell lines were cultured.The genomic DNA of the two cell lines were isolated by QIAamp DNA Blood Minikit.SNP genotyping of DPYD gene rs1801159,rs1801160,rs17376848 and MTHFR gene rs1801131,rs1801133,rs2274976 was performed by means of matrix assisted laser desorption ionisation-time of flight mass spectrometry method(MALDI-TOFMS).Results The genotypes of DPYD gene locus rs1801159 and rs1801160 were A/A and G/G respectively in the 3 cell lines.The genotype of DPYD gene locus rs17376848 was A/G in CFPAC cell line,While that were A/A in PANC-1 and SW1990 cell lines.The genotypes of MTHFR gene locus rs1801131 were A/C in PANC-1 and CFPAC cell lines,While that was A/A in SW1990 cell line.The genotypes of MTHFR gene locus rs1801133 were C/C in PANC-1 and CFPAC cell lines,While that was T/T in SW1990 cell line.The genotype of MTHFR gene locus rs2274976 was G/G in the above 3 cell lines.Conclusion Loci rs1801159,rs1801160 of DPYD gene and locus rs2274976 of MTHFR gene were same in the detected 3 cell lines.While other detected loci of DPYD and MTHFR gene in the 3 cell lines were expressed differently." @default.
- W2384009162 created "2016-06-24" @default.
- W2384009162 creator A5032249239 @default.
- W2384009162 date "2011-01-01" @default.
- W2384009162 modified "2023-10-18" @default.
- W2384009162 title "Analysis of single nucleotide polymorphisms of MTHFR and DPYD genes in pancreatic cancer cell lines" @default.
- W2384009162 hasPublicationYear "2011" @default.
- W2384009162 type Work @default.
- W2384009162 sameAs 2384009162 @default.
- W2384009162 citedByCount "0" @default.
- W2384009162 crossrefType "journal-article" @default.
- W2384009162 hasAuthorship W2384009162A5032249239 @default.
- W2384009162 hasConcept C104317684 @default.
- W2384009162 hasConcept C135763542 @default.
- W2384009162 hasConcept C153209595 @default.
- W2384009162 hasConcept C153911025 @default.
- W2384009162 hasConcept C2779655350 @default.
- W2384009162 hasConcept C31467283 @default.
- W2384009162 hasConcept C43563269 @default.
- W2384009162 hasConcept C54355233 @default.
- W2384009162 hasConcept C55775858 @default.
- W2384009162 hasConcept C84597430 @default.
- W2384009162 hasConcept C86803240 @default.
- W2384009162 hasConceptScore W2384009162C104317684 @default.
- W2384009162 hasConceptScore W2384009162C135763542 @default.
- W2384009162 hasConceptScore W2384009162C153209595 @default.
- W2384009162 hasConceptScore W2384009162C153911025 @default.
- W2384009162 hasConceptScore W2384009162C2779655350 @default.
- W2384009162 hasConceptScore W2384009162C31467283 @default.
- W2384009162 hasConceptScore W2384009162C43563269 @default.
- W2384009162 hasConceptScore W2384009162C54355233 @default.
- W2384009162 hasConceptScore W2384009162C55775858 @default.
- W2384009162 hasConceptScore W2384009162C84597430 @default.
- W2384009162 hasConceptScore W2384009162C86803240 @default.
- W2384009162 hasLocation W23840091621 @default.
- W2384009162 hasOpenAccess W2384009162 @default.
- W2384009162 hasPrimaryLocation W23840091621 @default.
- W2384009162 hasRelatedWork W1973264593 @default.
- W2384009162 hasRelatedWork W1995285916 @default.
- W2384009162 hasRelatedWork W2017016252 @default.
- W2384009162 hasRelatedWork W2020884248 @default.
- W2384009162 hasRelatedWork W2034342713 @default.
- W2384009162 hasRelatedWork W2041109030 @default.
- W2384009162 hasRelatedWork W2243510165 @default.
- W2384009162 hasRelatedWork W2355611195 @default.
- W2384009162 hasRelatedWork W2378246070 @default.
- W2384009162 hasRelatedWork W2387864873 @default.
- W2384009162 hasRelatedWork W2412781759 @default.
- W2384009162 hasRelatedWork W2581119348 @default.
- W2384009162 hasRelatedWork W2789353235 @default.
- W2384009162 hasRelatedWork W2883806651 @default.
- W2384009162 hasRelatedWork W3015188186 @default.
- W2384009162 hasRelatedWork W3047023128 @default.
- W2384009162 hasRelatedWork W194663866 @default.
- W2384009162 hasRelatedWork W2861317484 @default.
- W2384009162 hasRelatedWork W2867400181 @default.
- W2384009162 hasRelatedWork W2983459991 @default.
- W2384009162 isParatext "false" @default.
- W2384009162 isRetracted "false" @default.
- W2384009162 magId "2384009162" @default.
- W2384009162 workType "article" @default.