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- W2384013040 abstract "OBJECTIVE:To study the antioxidation of vitamin E and/orβ—carotene on mice induced by radiation.METHODS:Mice were divided randomly into 5 groups of normal control,positive,vitamin E,β-carotene, vitamin E plusβ-carotene.All of the animals except the normal control were irradiated with 4.5 Gy of ~(60)Coγ.After the radiation,the vitamin supplementation animals were given vitamin E[30 mg/(kg·d)]and/orβ—carotene[20 mg/(kg·d)]. Three days later,the animals were sacrificed.The retinol binding protein(RBP) in serum was analyzed with enzyme-linked immunosorbent assay(ELISA),and the levels of malondialdehyde(MDA) and reduced glutathione(GSH) in serum and liver were determined with fluorometry.RESULTS:~(60)Coγradiation decreased the level of RBP in serum.Supplementation of vitamin E and/orβ-carotene showed certain protection.Vitamin E and/orβ-carotene also inhibited the increase of MDA and the decrease of GSH in serum and liver induced by ~(60)Coγradiation.Vitamin E alone showed the best protection. CONCLUSION:Both vitamin E andβ-carotene showed protective effects on the oxidative injuries in mice induced by radiation.But the combined use of vitamin E andβ-Carotene showed antagonistic rather than synergistic effect." @default.
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- W2384013040 date "2011-01-01" @default.
- W2384013040 modified "2023-09-25" @default.
- W2384013040 title "Combined effects of vitamin E andβ-carotene on radiation injuries in mice" @default.
- W2384013040 hasPublicationYear "2011" @default.
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